Skip to content
Great news for kids: OSSIOfiber® Metal-Free Compression Screws and Trimmable Fixation Nails are now FDA cleared for various bone fractures in children (ages 2-12) and adolescents (ages 12-21). Read More


Learn more about intelligent bone regeneration with OSSIOfiber®

Implant-related artifacts around metallic and bio-integrative screws: a CT scan 3D Hounsfield unit assessment

Christian VandeLune1, Tutku Tazegul1, Samuel J Ahrenholz1, Caleb Iehl1, Victoria Vivtcharenko1, Eli Schmidt1, Kevin N Dibbern1, Hee Young Lee1, Matthieu Lalevee1, Nacime Salomão Barbachan Mansur1, César de César Netto1 1. Department of Orthopedics and Rehabilitation, University of Iowa, Carver College of Medicine, Iowa City-IA, USA. Study performed at Department of Orthopedics and Rehabilitation, University ofContinue reading “Implant-related artifacts around metallic and bio-integrative screws: a CT scan 3D Hounsfield unit assessment”

Department of Orthopedics and Rehabilitation, University of Iowa, Carver College of Medicine, Iowa City-IA, USA. October 4, 2021

First-in-Human, Prospective, Multicenter Clinical Study

OSSIO is thrilled to announce the publication of our prospective, multicenter, first-in-human clinical trial in Foot & Ankle Orthopaedics.  Prospective, Multicenter, Clinical and Radiographic Evaluation of a Biointegrative, Fiber-Reinforced Implant for Proximal Interphalangeal Joint ArthrodesisLuke D. Cicchinelli, DPM, Jurij Štalc, MD, Martinus Richter, MD, PhD, Stuart Miller, MD Twenty-five patients underwent PIPJ fusions with OSSIOfiber HammertoeContinue reading “First-in-Human, Prospective, Multicenter Clinical Study”

In Vivo Study of Bio-Integrative OSSIOfiber Plates

The performance and bio-integration of the OSSIOfiber® Intelligent Bone Regeneration Technology has been successfully evaluated for in-bone and soft tissue fixation. The purpose of this in vivo study was to further evaluate the OSSIOfiber® material properties when implanted over the surface of bone, for its bone-implant interface, local tissue response and full bio-integration profile. ThisContinue reading “In Vivo Study of Bio-Integrative OSSIOfiber Plates”

Co-Principal Investigator’s Overview of First-in-Human Clinical Study

The first-in-human clinical study for OSSIOfiber Intelligent Bone Regeneration Technology was a multicenter, prospective, single-arm study designed to primarily focus on proving the safety and efficacy of the material technology for hammertoe correction arthrodesis.  At 6 months, the study’s results were published in Foot & Ankle Orthopaedic Journal. Hear co-principal investigator, Luke Cicchinelli, DPM, speakContinue reading “Co-Principal Investigator’s Overview of First-in-Human Clinical Study”

Luke Cicchinelli, DPM November 3, 2020

ASPS Webinar

Earn CECH credits by watching this recent webinar, hosted with American Society of Podiatric Surgeons and presenter Bob Baravarian, DPM, FACFAS.  NOW ON-DEMAND WEBINAR: The Science and Clinical Experience with Strong and Bio-Integrative Implant Fixation Speaker: Bob Baravarian, DPM, FACFAS   Hear Dr. Baravarian present on: Science behind the strong and bio-integrative OSSIOfiber Technology First-in-humanContinue reading “ASPS Webinar”

AOFAS Scientific ePoster

During the virtual 2020 AOFAS meeting, Greg Berlet, MD, presented a scientific ePoster on the bio-integration and bone fixation strength of OSSIOfiber Intelligent Bone Regeneration Technology. We invite you to read the ePoster! AOFAS Scientific ePoster Bio-Integration and Bone Fixation Performance of Continuous Mineral Fiber-Reinforced Implants Authors: Gregory Berlet, MD, FRCS(C), FAOARonit Merchav-Feuermann, DVMNicolette DContinue reading “AOFAS Scientific ePoster”

Interested in OSSIOfiber®?

Complete the form and an OSSIOfiber® Advisor will get in touch.

Customer Service

For product inquiries or purchasing questions contact 833-781-7373 or email


Commercial Headquarters
300 Tradecenter Drive, Suite 3690
Woburn, MA, 01801

Science & Manufacturing Center

8 HaTochen Street
Cesarea, Israel 3079861

OSSIOfiber® has been used by over 900 surgeons across the US


1. Data on file at OSSIO 2. Clinical study data on file at OSSIO 3. Kaiser, P.B., Watkins, I., Riedel, M. D., Cronin, P., Briceno, J., Kron, J. Y. (2019). Implant Removal Matrix for the Foot and Ankle Orthopaedic Surgeon. Foot & Ankle Specialist, 12(1), 79-97. 4. Pre-clinical animal studies (in-bone implantation of OSSIOfiber® and PLDLA control in rabbit femurs). Data on File at OSSIO. 5. Haddad, S. F., Helm, M. M., Meath, B., Adams, C., Packianathan, N., & Uhl, R. (2019). Exploring the Incidence, Implications, and Relevance of Metal Allergy to Orthopaedic Surgeons. Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 3(4), e023. 6. Pot J, Wensen RV, Olsman J. Hardware Related Pain and Hardware Removal after Open Reduction and Internal Fixation of Ankle Fractures. The Foot and Ankle Online Journal. 2011;4(5). doi:10.3827/ faoj.2011.0405.0001.