The Science Behind OSSIOfiber®

OSSIOfiber® Intelligent Bone Regeneration Technology

Why Bio-Integrative Fixation?

 

Bio-Integrative OSSIOfiber® is a breakthrough fixation material technology that provides the first credible solution to the shortcomings of permanent metal hardware, conventional resorbable and allograft implants.

It’s stronger than cortical bone, stronger and more predictable than polymers alone, and without the foreign body reactions, stress-shielding, and potential patient discomfort or removal risks commonly associated with permanent metal hardware.

Strong and Bio-Integrative OSSIOfiber® implants provide a unique matrix of fibers made from minerals like those already found in bones to support strong fixation and enable early bone attachment, gradual bone and tissue ingrowth, and complete integration, all without local or systemic adverse response.

OSSIOfiber ® offers surgeons and patients the confidence and certainty of a fully Bio-Integrative solution that utilizes existing reimbursement and surgical techniques and provides a more natural healing environment.

Strong, Secure Fixation

Bone In-Growth, Regeneration, and Replacement

Avoids Risks and Costs Associated with Permanent Implants

Vast Surgical Applications

Utilizes Existing Reimbursement and Surgical Technique

Proven Materials in a Strong and Biointegrative Matrix

Engineered for rapid bone in-growth, regeneration and replacement

For illustrative purposes only
For illustrative purposes only

50% Natural Mineral Fibers 

Enhanced mechanical strength and fluid flow for progressive bone integration

  • Composed of silica, magnesium, calcium, and other natural minerals found in bone
  • Mineral have been in clinical use for over 30 years, most commonly as osteoconductive bone void fillers

50% Polymer

Limited Polymer for more predictable integration into the local area without adverse inflammation

  • Poly (L-lactide-co-D,L-lactide) (PLDLA) binds the fiber matrix together
  • PLDLA has over 30 years of clinical success and can be gradually and naturally cleared by the body through hydrolysis

Learn More About the Material Composition and Design

OSSIOfiber® Technology White Paper

The Science Behind OSSIOfiber®

Strong and
Bio-Integrative Fixation

Restore, Regrow, and Renew bone without permanent metal hardware

1.5X STRONGER THAN CORTICAL BONE1

EARLY BONE ATTACHMENT IN AS LITTLE AS 2 WEEKS2

FAVORABLE, NATURAL ENVIRONMENT FOR BONE REGENERATION1

RESTORE – TIME 0

Secure, initial fixation with strength 1.5x greater than healthy cortical bone1

REGROW – 2-26 WEEKS

Appropriate fixation strength during gradual integration, enables load sharing during healing and rehabilitation1

RENEW – 78-104 WEEKS

Full integration into surrounding anatomy without adverse inflammation2only nature remains

1. Data on File at OSSIO
2. Pre-clinical animal studies (in-bone implantation of OSSIOfiber and PLDLA control in rabbit femurs). Data on File at OSSIO

OSSIOfiber® vs

Metal

A non-permanent alternative that offers all the necessary strength and full Bio-Integration

SECURE INITIAL FIXATION

GRADUAL LOAD SHARING AVOIDS STRESS-SHIELDING

AVOID SECONDARY REPAIR AND REMOVAL PROCEDURES

ARTIFACT-FREE IN X-RAY/CT, MRI SAFE

Data on File at OSSIO

SEE FUSION, NOT HARDWARE

The X-rays are of two similar patients who underwent an identical surgical approach. One patient was treated with bio-Integrative OSSIOfiber® while the other was treated with traditional metal compression screws.*

 

*Results from case studies are not are not predictive of results. Results may vary

OSSIOfiber® vs

Resorbables

A proprietary fiber matrix for superior strength and Bio-Integration

5X STRONGER THAN COMMON RESORBABLES1

GRADUAL AND PREDICTABLE INTEGRATION

NO DELAYED ADVERSE INFLAMMATORY RESPONSE

1. Data on File at OSSIO

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Address

Commercial Headquarters

OSSIO Inc
300 TradeCenter, Suite 3690
Woburn, MA. 01801

Science & Technology Center

OSSIO Ltd.
8 HaTochen Street.
Caesarea, Israel 3079861

Customer Service

For product inquiries or purchasing questions contact 833-781-7373 or email info@ossio.io